Keywords
dental implants
titanium implants
biomaterials
protein adsorption
How to Cite
Abstract
Introduction: Osseointegration is a process that allows the interaction of titanium implants with bone tissue. This interface is permeated by a protein anchoring so that the biomaterial is not in direct contact with the periosteum. Objective: This literature review aims to present the process of protein adsorption in osseointegrated implants, highlighting the main proteins that participate in this process. Methodology: The search was conducted on the PubMed, SciELO and Google Academic platforms with articles published between 2008 and 2022 in Portuguese and English. Results: Soon after implant installation, a provisional fibrin matrix is formed (angiogenesis process) that precedes osseointegration. Afterwards, in the osteoconduction space, there is an interaction between the titanium implant surface and proteins from the cell membrane. Thus, this protein interaction will support the peri-implant ligament. However, different factors such as implant surface properties and protein properties may influence this adsorption process. Conclusion: In this sense, it can be assumed that protein adsorption is an indispensable mechanism for successful osseointegration in titanium and titanium alloy implants.
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Copyright (c) 2022 Ana Carolina Rosa de Almeida, Nicole Serqueira da Silva, Marvin Nascimento, Bruno Martins de Souza, Aline Tany Posh