Desafios no diagnóstico da doença de Alzheimer

Abstract

Introduction: Alzheimer’s Disease (AD) is a progressive neurodegenerative condition that affects millions of people worldwide, being the most common form of dementia. The diagnosis of AD is challenging due to the overlap of symptoms, the lack of specific biomarkers, and the variability in clinical presentation. Investing in research to develop more accurate biomarkers and imaging techniques is crucial for improving the diagnosis and treatment of the disease. Objective: To understand the challenges in diagnosing Alzheimer’s disease. Methodology: included reading selected articles from scientific databases such as Google Scholar, PubMed, BVS, and SCIELO, with rigorous inclusion criteria. Original articles published between 2016 and 2024 were considered, addressing the research topic comprehensively. Results: highlight the challenges in diagnosing AD, such as the overlap of symptoms with other conditions, the lack of specific biomarkers, and the variability in clinical presentation. Treatment has evolved, focusing on the underlying causes of the disease. Promising therapies include the use of monoclonal antibodies to target beta-amyloid plaques in the brain and the development of vaccines that stimulate the immune system to attack the plaques. Final Considerations: In summary, AD is a devastating condition that requires innovative therapeutic and preventive approaches. Collaboration among scientists, physicians, and communities is essential to tackle this complex and debilitating disease. Ongoing research is vital for advancing the understanding and treatment of AD.