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Abstract
This study examines promising therapeutics for obesity control, addressing a variety of innovative and integrated approaches. Initially, the potential of pharmacological therapies, such as GLP-1 receptor agonists and SGLT-2 inhibitors, is highlighted, showcasing their effectiveness in weight reduction and improved glycemic control. Furthermore, the growing interest in interventions centered on the intestinal microbiota is emphasized, elucidating how manipulating bacterial composition can influence metabolism and contribute to weight loss.
Another notable aspect is the role of metabolic modulation therapies, such as blood flow restriction during exercise, with evidence indicating improvements in neural reactivity to food stimuli in obese individuals. Following this, behavioral strategies and psychological therapies, including cognitive-behavioral therapy and the promotion of healthy eating habits, are discussed as essential elements in the sustainable control of obesity over time.
In addition to pharmacological approaches, microbiota modulation, and behavioral strategies, this study underscores the need for a holistic understanding of obesity. The importance of incorporating personalized interventions, considering genetic, metabolic, and socioeconomic factors influencing an individual's response to proposed therapeutics, is emphasized. Adopting a patient-centered approach, the study highlights the necessity for continuous care and support over time, acknowledging the complexity of obesity control. In this regard, the research emphasizes not only the effectiveness of therapeutics but also the need for an integrated and personalized approach to comprehensively address this health challenge.
Finally, the importance of a multidisciplinary approach is emphasized, integrating different therapeutics to optimize outcomes in obesity control. The combination of pharmacological interventions, microbiota modulation, behavioral strategies, and psychological support emerges as a comprehensive and promising approach to tackle this global health challenge.
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Copyright (c) 2024 Nilra Beatriz Pereira Dias Ribeiro, Maria Alice Marques Pinheiro, Marcos Renon Vogado Nogueira , Tábata Cléia Alves de Freitas , Laryssa Graziele Barbosa Miranda , Victória Albani Cassa, Jessica Luísa Moretto , César Barreiros Vieira Perez , Henrique Luchi Roldi , Ana Karla Alves do Carmo , Vitória Fedeszen Mozdzen , Brenda Dias do Nascimento , Júlia Rodrigues de Senna Mendonça , Antonio Emílio Couto Fardin
