ROLE OF CUTANEOUS CYTOKINES IN PSORIASIS AND PREGNANCY: AN IMMUNOLOGICAL PERSPECTIVE
DOI:
https://doi.org/10.36557/2674-8169.2023v5n5p5422-54243Keywords:
Psoriasis; Pregnancy; Cytokines; Immunology.Abstract
Introduction: The relationship between pregnancy and psoriasis is observed, as several studies and research indicate a direct relationship, in which immunological variations generated by pregnancy end up affecting and influencing the aforementioned disease. Those responsible for the skin's immunological reactions are Cytokines. Objective: Understand how Cytokine proteins act in relation to psoriasis in pregnant women. Methodology: A systematic literature review was carried out covering the years from January 2003 to December 2023. The study was based and guided by the question mentioned throughout the article. Results: Starting from the point that pregnant women present several immunological changes so that they can generate sustainability for the growth of the fetus, an increase in the number of so-called anti-inflammatory cytokines is noted, for example beta (TGF), which can reduce the psoriasis inflammation process. On the other hand, there are other types of Cytokine proteins that end up triggering and aggravating peeling and inflammatory lesions. Conclusion: Pregnant women end up having limitations to psoriasis treatments, since in most cases a personalized care strategy plan is needed according to the individual's clinical status and insurance so that it is possible that no type of complication occurs.
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Acadêmica V, Curitiba. MEDICAMENTOS BIOLÓGICOS UTILIZADOS EM PSORÍASE MODERADA A GRAVE - UMA REVISÃO DA EVIDÊNCIA CLÍNICA BIOLOGIC MEDICINES FOR MODERATE TO SEVERE PSORIASIS -A REVIEW OF CLINICAL EVIDENCE 1 1 2. [cited 2023 Dec 14];(2). Available from: https://revistas.ufpr.br/academica/article/download/31119/20128
Castilho AC da S, Lopes C de OP, Salles BCC. Fisiopatologia da psoríase e seus aspectos imunológicos: uma revisão sistemática. Research, Society and Development. 2021 Aug 30;10(11):e256101119346.
Certolizumabe pegol para o tratamento de pacientes com psoríase em placas moderada a grave Brasília -DF 2022 [Internet]. [cited 2023 Dec 14]. Available from: https://fi-admin.bvsalud.org/document/view/9kv9h
Geral C, Pires C, Maia A, Denise M, Takahashi F, Romiti R. 2 a Edição CONSENSO BRASILEIRO DE PSORÍASE 2012 SOCIEDADE BRASILEIRA DE DERMATOLOGIA [Internet]. Available from: https://www.saudedireta.com.br/docsupload/1377775822Consenso_Psoriase_2012.pdf
Gleison V, Duarte. Avaliação de marcadores clínicos e biológicos associados com a Psoríase Vulgar UNIVERSIDADE FEDERAL DA BAHIA PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE -PPgCS CURSO DE DOUTORADO EM CIÊNCIAS DA SAÚDE [Internet]. Available from: https://repositorio.ufba.br/bitstream/ri/24389/1/Tese_ICS_Gleison%20Vieira%20Duarte.pdf
Lima E de A, Lima M de A. Imunopatogênese da psoríase: revisando conceitos. Anais Brasileiros de Dermatologia. 2011 Dec;86(6):1151–8.
MINISTÉRIO DA SAÚDE SECRETARIA DE ATENÇÃO ESPECIALIZADA À SAÚDE SECRETARIA DE CIÊNCIA, TECNOLOGIA E INSUMOS ESTRATÉGICOS EM SAÚDE PORTARIA CONJUNTA No 18, de 14 de outubro [Internet]. Available from: https://www.gov.br/saude/pt-br/assuntos/protocolos-clinicos-e-diretrizes-terapeuticas-pcdt/arquivos/2019/PortariaConjuntan18de14102021_PCDT_Psoriase.pdf
Prado E, Pastorino AC, Harari DK, Mello MC, Chong-Neto H, Carvalho VO, et al. Dermatite atópica grave: guia prático de tratamento da Associação Brasileira de Alergia e Imunologia e Sociedade Brasileira de Pediatria. Arquivos de Asmas Alergia e Imunologia. 2022;6(4).
PSORÍASE 2020 ALGORITMO DE TRATAMENTO DA SOCIEDADE BRASILEIRA DE DERMATOLOGIA [Internet]. Available from: https://www.biosanas.com.br/uploads/outros/artigos_cientificos/152/770a01deea02365ae98071043abd3f12.pdf
Rodrigues TSV, Gomes LC, Cortela DCB, Silva EA, Silva CAL, Ferreira SMB. Factors associated with leprosy in children contacts of notified adults in an endemic region of Midwest Brazil. Jornal de Pediatria. 2020 Sep;96(5):593–9.
Sanchez APG. Imunopatogênese da psoríase. Anais Brasileiros de Dermatologia [Internet]. 2010 Oct 1;85:747–9. Available from: https://www.scielo.br/j/abd/a/jQKC3wrwd9LyY3dWSX44zjB/?lang=pt
SUELI COELHO DA SILVA CARNEIRO Psoríase: mecanismos de doença e implicações terapêuticas [Internet]. Available from: https://www.teses.usp.br/teses/disponiveis/livredocencia/5/tde-16032009-152131/publico/SueliCarneiroLD.pdf
Soares V, Bastos E, Kátia P, De R, Callou A. Saberes e práticas em psoríase DA CIÊNCIA AO cuidado AO [Internet]. [cited 2023 Dec 14]. Available from: http://www.editora.ufpb.br/sistema/press5/index.php/UFPB/catalog/download/690/885/7030-1?inline=1
Sousa C, Fernando Pessoa U. A Psoríase [Internet]. Available from: https://bdigital.ufp.pt/bitstream/10284/7096/3/PPG_29467.pdf
Teixeira P, Felipe E, Cardoso S, Vinagre C, Franco P, Vinagre V, et al. TRATAMENTO DA PSORÍASE EM ADULTOS: REVISÃO DE LITERATURA PSORIASIS TREATMENT IN ADULTS: A LITERATURE REVIEW TRATAMIENTO DE LA PSORIASIS EN ADULTOS: REVISIÓN DE LA LITERATURA. [cited 2023 Dec 14]; Available from: https://recima21.com.br/index.php/recima21/article/download/3326/2517
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Copyright (c) 2023 Sávio Dimas da Silva , Maria Eduarda de Sá Bonifácio Rocha , Hosana Maria Araújo Rêgo , Leticia Dantas Trindade , Felipe Alberto Dantas Pinto de Paiva , Gabriel Rozendo Mendonça Gomes, Lizandra Cunha de Carvalho , Matheus Bezerra Gondim, Vitória França de Oliveira Oporto , Rogério Batista Montenegro, Laísa Gomes Salvador , Thiago Maio Bandeira , Beatriz yumi Osaki Chikui , Gabriella Pinheiro Castro Sampaio , Laís Cardozo Barreto
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