Resumo
O surgimento do SARS-CoV-2 trouxe desafios significativos para a Odontologia, especialmente por se tratar de uma profissão que exige proximidade física entre o profissional e o paciente, além da produção constante de aerossóis durante os procedimentos. Esses fatores aumentam o risco de transmissão de doenças infecciosas, especialmente em ambientes como consultórios odontológicos, onde as principais vias de contágio – boca, nariz e olhos – ficam constantemente expostas. Diante desse cenário, tornou-se essencial investigar estratégias eficazes de prevenção da contaminação cruzada, como o uso de enxaguatórios bucais antivirais, métodos de desinfecção de superfícies e a atualização dos equipamentos de proteção individual. Para isso, foi realizada uma pesquisa eletrônica na base de dados PubMed, com artigos publicados até agosto de 2020, utilizando os termos “Covid-19” + “Dentistry” e “SARS-CoV-2” + “Dentistry”. Inicialmente, foram encontrados 537 estudos. Após análise de títulos e resumos, 92 foram selecionados, e, desses, 67 apresentaram relação direta com o escopo da revisão. Os resultados demonstraram que o peróxido de hidrogênio a 1% e a iodopovidona a 0,2% foram os enxaguatórios bucais mais eficazes na redução da carga viral. Já na desinfecção de superfícies, soluções à base de álcool e hipoclorito mostraram efeito significativo na inativação do vírus. Esses achados reforçam a importância de medidas preventivas rigorosas na rotina odontológica. A implementação de protocolos baseados em evidências científicas, aliada à disseminação de orientações claras aos profissionais da área, é fundamental para reduzir os riscos de contaminação e, consequentemente, controlar a curva de infecção no ambiente clínico.
Referências
Meng L, Hua F, Bian Z. Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine. J Dent Res. 2020;99(5):481-7.
Maffia F, Fontanari M, Vellone V, Cascone P, Mercuri LG. Impact of COVID-19 on maxillofacial surgery practice: a worldwide survey. Int J Oral Maxillofac Surg. 2020;49(6):827-35.
Fallahi HR, Keyhan SO, Zandian D, Kim SG, Cheshmi B. Being a front-line dentist during the Covid-19 pandemic: a literature review. MaxillofacPlastReconstrSurg. 2020 Apr24;42(1):12.
Xian Peng, XinXu, Yuqing Li, Lei Cheng, Xuedong Zhou, Biao Ren Transmission routes of 2019-nCoV and controls in dental practic. Int J Oral Sci. 2020;12: 9.
Sabino-Silva R, Jardim ACG, Siqueira WL. Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis. Clin Oral Investig. 2020;24(4):1619-21. doi:10.1007/s00784-020-03248-x.
Fini MB. Oral saliva and COVID-19. Oral Oncol. 2020;108:104821. doi:10.1016/j.oraloncology.2020.10482.
Spagnuolo G, De Vito D, Rengo S, Tatullo M. COVID-19 Outbreak: An Overview on Dentistry. Int J Environ Res Public Health. 2020;17(6):2094. doi:10.3390/ijerph17062094.
Santosh TS,Parmar R, Anand H, Srikanth K, Cureus MS. A Review of Salivary Diagnostics and Its Potential Implication in Detection of Covid-19. 2020 Apr; 12(4):e7708.
Ge ZY, Yang LM, Xia JJ, Fu XH, Zhang YZ. Possible aerosol transmission of COVID-19 and special precautions in dentistry. J Zhejiang UnivSci B. 2020 May;21(5):361-8.
Guo J, Xie H, Liang M, Wu H. COVID-19: a novel coronavirus and a novel challenge for oral healthcare. Clin Oral Investig. 2020;24(6):2137-8. doi:10.1007/s00784-020-03291-8.
Zhao Z, Gao D.Precaution of 2019 novel coronavirus infection in department of oral and maxillofacial surgery. J Oral Maxillofac Surg. 2020 Apr; 58(3): 250-3.
Wilkins T, Gillies RA, Davies K. EMBASE versus MEDLINE for family medicine searches: can MEDLINE searches find the forest or a tree? CanFamPhysician. 2005 Jun; 51:848-9.
Falagas ME, Pitsouni EI, Malietzis GA, Pappas G. Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses. FASEB J. 2008 Feb;22(2):338-42.
Kelly L, St Pierre-Hansen N. So many databases, such little clarity: Searching the literature for the topic aboriginal. CanFamPhysician. 2008 Nov;54(11):1572-3.
Hamid H, Khurshid Z, Adanir N, Zafar MS, Zohaib S. COVID-19 Pandemic and Role of Human Saliva as a Testing Biofluid in Point-of-Care Technology. Eur J Dent. 2020 Jun 3. doi: 10.1055/s-0040-1713020.
Gugnani N, Gugnani S. Safety protocols for dental practices in the COVID-19 era. Evid Based Dent. 2020 Jun;21(2):56-57. doi: 10.1038/s41432-020-0094-6.
Vinayachandran D, Saravanakarthikeyan B. Salivary diagnostics in COVID-19: Future research implications. J Dent Sci. 2020 Apr 23. doi: 10.1016/j.jds.2020.04.006.
Han P, Ivanovski S. Saliva-Friend and Foe in the COVID-19 Outbreak.2020 May 9;10(5):290. doi: 10.3390/diagnostics10050290.
To KK, Tsang OT, Leung WS, et al Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020;20(5):565-74. doi:10.1016/S1473-3099(20)30196.
Kohn WG, Collin AS, Cleveland JL, Harte JA, Eklund KJ, Malvitz DM, Centers for Disease Control and Prevention (CDC). (2003). Guidelines for infection control in dental health-care settings--2003. MMWR Recomm Rep. 2003 Dec 19;52(RR-17):1-61.
Wadia R. Transmission routes of COVID-19 in the dental practice. BrDent J.2020 Apr;228(8):595. doi: 10.1038/s41415-020-1547-1.
Carrouel F, Conte MP, Fisher J, et al COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. J Clin Med. 2020;9(4):1126. doi:10.3390/jcm9041126.
Fini MB.What dentists need to know about COVID-19. Oral Oncol. 2020 Jun; 105:104741. doi:10.1016/j.oraloncology.2020.104741.
Gugnani N, Gugnani S. Safety protocols for dental practices in the COVID-19 era. Evid Based Dent. 2020 Jun;21(2):56-57. doi: 10.1038/s41432-020-0094-6.
Maffia F, Fontanari M, Vellone V, Cascone P, Mercuri LG. Impact of COVID-19 on maxillofacial surgery practice: a worldwide survey. Int J Oral Maxillofac Surg. 2020;49(6):827-35. doi: 10.1016/j.ijom.2020.04.015.
American Dental Association. ADA Interim Guidance for Minimizing Risk of COVID-19 Transmission. Available from: https://www.ada.org/~/media/CPS/Files/COVID/ADA_COVID_Int_Guidance_Treat_Pts.pdf. Accessed May 10, 2020.
Martínez Lamas L, Diz Dios P, Pérez Rodríguez MT, et alIs povidone iodine mouthwash effective against SARS-CoV-2? First in vivo tests. Oral Dis. 2020;10.1111/odi.13526. doi:10.1111/odi.13526.
Zhou R, Li F, Chen F, et al Viral dynamics in asymptomatic patients with COVID-19. Int J Infect Dis. 2020;96:288-90. doi: 10.1016/j.ijid.2020.05.030.
Chin AWH, Chu JTS, Perera MRA, et al Stability of SARS-CoV-2 in different environmental conditions. Lancet Microbe. 2020;1(1):e10. doi:10.1016/S2666-5247(20)30003-3.
Bidra AS, Pelletier JS, Westover JB, Frank S, Brown SM, Tessema B. Comparison of In Vitro Inactivation of SARS CoV-2 with Hydrogen Peroxide and Povidone-Iodine Oral Antiseptic Rinses. J Prosthodont. 2020 Jun 30:10.1111/jopr.13220. doi: 10.1111/jopr.13220. Epub ahead of print. PMID: 32608097; PMCID: PMC7361576.
Marui VC, Souto MLS, Rovai ES, Romito GA, Chambrone L, Pannuti CM. Efficacy of preproceduralmouthrinses in the reduction of microorganisms in aerosol: A systematic review. J AmDent Assoc. 2019;150(12):1015-26.e1. doi:10.1016/j.adaj.2019.06.024.
Yoon JG, Yoon J, Song JY, et al Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva. J Korean Med Sci. 2020;35(20):e195. doi:10.3346/jkms.2020.35.e195.
Jorge AOC. Princípios de Biossegurança em Odontologia. RevBiociên. 2002:8(1):7-17.
Silva CRG, Jorge AOC. Avaliação de desinfecção de superfície utilizada em Odontologia. PesquiOdontol Bras. 2002;16(2):107-14.
Martins-Filho PR, de Gois-Santos VT, Tavares CSS, de Melo EGM, do Nascimento-Júnior EM, Santos VS. Recommendations for a safety dental care management during SARS-CoV-2 pandemic. Rev Panam Salud Publica. 2020;44:e51. doi:10.26633/RPSP.2020.51.
Rabenau H.F, Cinatl J, Morgenstern B, Bauer G, Preiser W, Doerr HW. Stabilityandinativationof SARS Coronavírus. MedMicrobiolImmunol. 2005;194:1-6.
Ortega KL, Camargo AR, Franco JB, Azul AM, Sayáns MP, Silva PHB. SARS-CoV-2 anddentistry. Clin Oral Investig. 2020 Jun 5:1-2.doi: 10.1007/s00784-020-03381-7.
Kampf G, Todt D, Pfaender S. Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hosp Infect. 2020;104(3): 246-51.
Duan SM, Zhao XS, Wen RF, et al Stability of SARS coronavirus in human specimens and environment and its sensitivity to heating and UV irradiation. Biomed Environ Sci. 2003;16(3):246-55.
Lai M.Y, Cheng P.K, Lim W.W. Sobrevivência de Coronavírus com síndrome respiratória aguda grave. Clin. Infectar. Dis. 2005;41:67-71.
Chen YC, Huang LM, Chan CC, Su CP, Chang SC, Chang YY, Chen ML, Hung CC, Chen WJ, Lin FY, et al SARS in Hospital EmergencyRoom. EmergInfectDis. 2004 May; 10(5):782-8.
Dowell SF, Simmerman JM, Erdman DD, et al Severe acute respiratory syndrome coronavirus on hospital surfaces. Clin Infect Dis. 2004;39(5):652-657. doi:10.1086/422652.
Yuen JW, Chung TW, Loke AY. Methicillin-resistant Staphylococcus aureus (MRSA) contamination in bedside surfaces of a hospital ward and the potential effectiveness of enhanced disinfection with an antimicrobial polymer surfactant. Int J Environ Res Public Health. 2015;12(3):3026-41. doi:10.3390/ijerph120303026.
Chigurupati R, Panchal N, Henry AM, Batal H, Sethi A, D'innocenzo R, Mehra P, Krishnan DG, Roser SM. Considerations for Oral and Maxillofacial Surgeons in COVID-19 Era: Can We Sustain the Solutions to Keep Our Patients and Healthcare Personnel Safe? J Oral Maxillofac Surg. 2020 May 24;78(8):1241-56.
Kampf G, Todt D, Pfaender S. Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hosp Infect. 2020;104(3): 246-51.
Rutala W.A, Weber D.J, HICPAC. Guideline for disinfection and sterilization in healthcare facilities, GA: US Department of Health and Human Services, CDC; 2008.
Suchomel M, Eggers M, Maier S, Kramer A, Dancer SJ, Pittet D. Evaluation of World Health Organization-Recommended Hand Hygiene Formulations.EmergInfectDis. 2020;26(9):2064-8. doi:10.3201/eid2609.201761.
Busato CA, Cavazzola AS, Ortega AOL, Guaré RO, Neto AS. The use of sodium hypochlorite for toothbrushes decontamination: in vitro study. Rev Odontol UNESP. 2015 Dec;44(6):335-9. doi.org/10.1590/1807-2577.04214.
Pereira SSP, Oliveira HM, Turrini RNT, Lacerda RA. Disinfection with sodium hypochlorite in hospital environmental surfaces in the reduction of contamination and infection prevention: a systematic review. Rev Esc Enferm USP.·2015;49(4):681-8.
Bhanushali P, Katge F, Deshpande S, Chimata VK, Shetty S, Pradhan D. COVID-19: Changing Trends and Its Impact on Future of Dentistry. Int J Dent. 2020;2020:1-6.
Block MS, Rowan BG. Hypochlorous Acid: A Review. J Oral MaxillofacSurg. 2020;78(9):1461-6. doi:10.1016/j.joms.2020.06.029.
Long RH, Ward TD, Pruett ME, Coleman JF, Plaisance MC Jr. Modifications of emergency dental clinic protocols to combat COVID-19 transmission. Spec Care Dentist. 2020;40(3):219-26. doi:10.1111/scd.12472.
Geller C, Varbanov M, Duval RE. Human coronaviruses: insights into environmental resistance and its influence on the development of new antiseptic strategies. Viruses. 2012;4(11):3044-68.
Boyce JM, Guercia KA, Sullivan L, Havill NL, Fekieta R, Kozakiewicz J, Goffman D. Prospective cluster-controlled crossover trial to compare the impact of an improved hydrogen peroxide disinfectant and a quaternary ammonium-based disinfectant on surface contamination and health care outcomes. Am J Infect Control. 2017;45(9):1006-10.
Barbosa ASAA, Carneiro GS, Repullio LF, Silveira M, Silva SMUR, Vilani-Moreno FR. Efficacy of ethyl alcohol and quaternary ammonium in hospital medical equipment disinfection. RevEpidemiol Controle Infecç. 2018 Out-Dez;8(4):409-14.
Enwemeka CS, Bumah VV, Masson-Meyers DS. Light as a potential treatment for pandemic coronavirus infections: A perspective. J PhotochemPhotobiol B. 2020;207:111891. doi:10.1016/j.jphotobiol.2020.111891.
Lo Giudice R. The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) in Dentistry. Management of Biological Risk in Dental Practice. Int J Environ Res Public Health. 2020 Apr28;17(9):3067.
Van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI, Lloyd-Smith JO, de Wit E, Munster VJ. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med. 2020;382(16):1564-7.
Gugnani N, Gugnani S. Safety protocols for dental practices in the COVID-19 era. EvidBasedDent. 2020 Jun;21(2):56-7.
Peters MDJ, Marnie C, Butler A. Policies and procedures for personal protective equipment: Does inconsistency increase risk of contamination and infection? Int J Nurs Stud. 2020;103653. doi: 10.1016/j.ijnurstu.2020.103653.
Zimmermann M, Nkenke E. Approaches to the management of patients in oral and maxillofacial surgery during COVID-19 pandemic. J CraniomaxillofacSurg. 2020;48(5):521-6. doi:10.1016/j.jcms.2020.03.011.
Camargo MC, Martinez-Silveira MS, Lima AA, et alEffectiveness of the use of non-woven face mask to prevent coronavirus infections in the general population: a rapid systematic review.CienSaude Colet. 2020;25(9):3365-76. doi:10.1590/1413-81232020259.13622020.
Lepelletier D, Grandbastien B, Romano-Bertrand S, et alWhat face mask for what use in the context of COVID-19 pandemic? The French guidelines. J Hosp Infect. 2020;105(3):414-8. doi:10.1016/j.jhin.2020.04.036.
Swennen GRJ, Pottel L, Haers PE. Custom-made 3D-printed face masks in case of pandemic crisis situations with a lack of commercially available FFP2/3 masks.Int J Oral MaxillofacSurg. 2020;49(5):673-7.doi:10.1016/j.ijom.2020.03.015.
Nejatidanesh F, Khosravi Z, Goroohi H, Badrian H, Savabi O. Risk of Contamination of Different Areas of Dentist's Face During Dental Practices. Int J Prev Med. 2013;4(5):611-5.
French Society of Stomatology, Maxillo-Facial Surgery and Oral Surgery (SFSCMFCO). Practitioners specialized in oral health and coronavirus disease 2019: Professional guidelines from the French society of stomatology, maxillofacial surgery and oral surgery, to form a common front against the infectious risk. J Stomatol Oral MaxillofacSurg. 2020;121(2):155-8. doi:10.1016/j.jormas.2020.03.011.
Huh S. How to train health personnel to protect themselves from SARS-CoV-2 (novel coronavirus) infection when caring for a patient or suspected case. J EducEval Health Prof. 2020;17:10. doi:10.3352/jeehp.2020.17.10.

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Rafael Arantes Soares Reis, Gabriel da Silva Costa, Ana Luísa Castro, Caroline Weinert Marçal, Marcos Pereira Villa-Nova, Matheus Canova Machado