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Este artigo revisa a literatura atual sobre os efeitos do uso prolongado de inibidores seletivos da recaptação de serotonina (ISRS) na homeostase glicêmica em pacientes sem diagnóstico prévio de diabetes. A seleção dos artigos foi realizada utilizando as bases de dados PubMed, Scopus e Web of Science, com os termos “Selective Serotonin Reuptake Inhibitors,” “Glycemic Homeostasis,” e “Non-Diabetic Patients.” A revisão abrange estudos recentes que investigam alterações nos níveis de glicose, resistência à insulina e secreção de insulina associadas ao uso crônico de ISRS. A conclusão aponta que o monitoramento regular, aliado a estratégias personalizadas de manejo terapêutico, pode mitigar os impactos adversos desses medicamentos, promovendo um equilíbrio entre eficácia no tratamento dos transtornos depressivos e segurança metabólica.
Referências
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